Transcriptome Encyclopedia of Early Human Development

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Transcriptome Encyclopedia of Early Human Development

Our understanding of human pre-implantation development is limited by the availability of human embryos and cannot completely rely on mouse studies. Petropoulos et al. now provide an extensive transcriptome analysis of a large number of human pre-implantation embryos at single-cell resolution, revealing previously unrecognized features unique to early human development.

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Encyclopedia of Infant and Early Childhood Development – Authors’ Instructions

Motor development may seem to be the simplest aspect of development but it is also the most complex one. To perform motor movements, children do not only need to acquire control over muscles; they also need to develop their perception, cognition, and motivation. Motor movements have to deal with the fact that events precede the feedback signals about them. The only way to overcome this problem ...

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Transcriptome Profiling of Human Pre-Implantation Development

BACKGROUND Preimplantation development is a crucial step in early human development. However, the molecular basis of human preimplantation development is not well known. METHODOLOGY By applying microarray on 397 human oocytes and embryos at six developmental stages, we studied the transcription dynamics during human preimplantation development. PRINCIPAL FINDINGS We found that the preimplan...

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ژورنال

عنوان ژورنال: Cell

سال: 2016

ISSN: 0092-8674

DOI: 10.1016/j.cell.2016.04.042